Orthopedic Regenerative

Cell Therapies

A better future is here for cartilage reconstruction


Solely focused on personalization, and pioneering autologous cell therapies for the treatment of joint cartilage injury and defects.

Get back to activity, get back to life...

Simple Procedure

No Artificial Elements

Long-term Outcomes

We offer advanced cartilage repair, restoration and transplant for athletes and other patients with cartilage injuries.

ReLive is pioneering regenerative cell therapies to address areas of orthopedic sports medicine and plastic and reconstructive surgery.

  • Over 25 years’ experience of tissue engineering
  • Over 200 hospitals using our products
  • Over 19,000 patients have been treated
  • Spherox is the only autologous cell therapy indicated for knee cartilage repair available for adults and pediatric patients*


* With a closed epiphyseal growth plate


orthopedic sports medical doctor


Outcomes You Can Trust


We have over 25 years` experience of tissue engineering and our product is currently the only cell based medicinal product indicated for knee cartilage repair and authorized by EMA. The efficacy and safety of the cell therapy have been demonstrated and confirmed in phase II and phase III clinical trials. Since the first treatment in 1997, ACI with spheroid technology has already been performed successfully with more than 18,000 patients – the evidence of the lasting success of our regenerative therapy approach. This is far more than a "proof of concept" - this is a real success story. 

Visible Repair on MRI


Magnetic Resonance Imaging (MRI) stands as a conventional non-invasive imaging modality utilized by surgeons for the visualization of cartilage tissue injuries and subsequent repair processes. Assessment of MRI scans of knee joints using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) Knee Scores subsequent to treatment with Spherox showcases substantial and enduring cartilage tissue restoration. This is substantiated by findings derived from Phase II and Phase III clinical studies


orthopedic sports medicine patient

Cartilage Repair

You Can Trust

We focus on personalization, autologous cell therapies for the treatment of joint cartilage defects.

How our Therapy Works
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