Our Platform Technology

Spheroid technology

We are at the forefront of innovation and a recognized leader in the field of spheroid technology. Our proprietary platform technology harnesses the remarkable power of a patient's own cells to create a groundbreaking autologous therapy designed to combat specific diseases. Spheroids, the cornerstone of our approach, represent exceptional "mini tissues" that undergo a remarkable transformation, self -assembling from a 2D monolayer into 3D spheres during cultivation process. What sets our spheroids apart is their innate programming to regenerate target tissues, making them a revolutionary force in biotechnology.

Using the example of an autologous product for the treatment of cartilage defects, the video shows how cartilage cells multiply and step by step self-assembling from a 2D monolayer into spheroids, 3D spheres consisting of autologous cartilage cells and matrix. One spheroid consists of at least 3,000 cells.

Autologous Chondrocyte Implantation (ACI) With Spheroid Technology
Spheroid technology is currently used to create Spherox, an autologous cell therapy for regenerative and minimally invasive treatment of joint cartilage defects in the knee. The treatment with the medical product is based on a surgical approach called matrix - associated autologous chondrocyte implantation (ACI).

Integrated Isolator Technology (IIT) – Clean Room Technology For Manufacturing Spheroids

The cell therapies for treating cartilage defects are manufactured in Germany, meeting or exceeding requirements to ensure and guarantee quality, purity and potency via thanks to state of the art integrated Isolator Technology (IIT). What makes this “clean room within a clean room” so special is that all the equipment required for producing transplants and for quality control is integrated in isolators that meet the highest clean room standards reducing possible contaminations to a minimum.